ISSN 2071-8594

Российская академия наук

Главный редактор

Академик С. В. Емельянов

Н.И. Базенков, Д.Д. Воронцов, В.Е. Дьяконова, Л.Ю. Жилякова, И.С. Захаров, О.П. Кузнецов, С.Г. Куливец, Д.А. Сахаров "Дискретное моделирование межнейронных взаимодействий в мультитрансмиттерных сетях"

Аннотация.

Предложена дискретная модель химических несинаптических взаимодействий между нейронами, осуществляемых специфическими химическими веществами – нейротрансмиттерами. В этой модели все сигналы являются широковещательными: активность каждого нейрона может быть воспринята всеми другими нейронами, чувствительными к его нейротрансмиттеру. Отсутствие синапсов призвано показать значимость роли гетерохимических 2 механизмов взаимодействия в нервных системах. Трансмиттер-специфические нейроны описываются в виде конечных автоматов, являющихся обобщением традиционного формального нейрона. В сети из таких нейронов все связи являются функциональными, а не структурными. Эта особенность позволяет объяснить быстрые механизмы перестройки паттернов активности при генерации разных ритмов нейронными ансамблями, наблюдаемые в живых системах. Обсуждается и обосновывается выбор дискретного аппарата для моделирования гетерохимических взаимодействий.

Ключевые слова:

дискретная динамика, гетерогенная нейронная система, гетерохимические взаимодействия, нейротрансмиттеры, нейромодуляция.

Стр. 55-73.

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